Van Gogh's early works consist of mostly still lifes and depictions of peasant labourers. In 1886, he moved to Paris, where he met members of the artistic avant-garde, including Émile Bernard and Paul Gauguin, who were seeking new paths beyond Impressionism. Frustrated in Paris and inspired by a growing spirit of artistic change and collaboration, in February 1888 van Gogh moved to Arles in southern France to establish an artistic retreat and commune. Once there, his paintings grew brighter and he turned his attention to the natural world, depicting local olive groves, wheat fields and sunflowers. Van Gogh invited Gauguin to join him in Arles and eagerly anticipated Gauguin's arrival in late 1888.

Van Gogh suffered from psychotic episodes and delusions. He worried about his mental stability, and often neglected his physical health, did not eat properly and drank heavily. His friendship with Gauguin ended after a confrontation with a razor when, in a rage, he severed his left ear. Van Gogh spent time in psychiatric hospitals, including a period at Saint-Rémy. After he discharged himself and moved to the Auberge Ravoux in Auvers-sur-Oise near Paris, he came under the care of the homeopathic doctor Paul Gachet. His depression persisted, and on 29 July 1890 van Gogh died from his injuries after shooting himself in the chest with a revolver.

Van Gogh's work began to attract critical artistic attention in the last year of his life. After his death, his art and life story captured public imagination as an emblem of misunderstood genius, due in large part to the efforts of his widowed sister-in-law Johanna van Gogh-Bonger. His bold use of colour, expressive line and thick application of paint inspired avant-garde artistic groups like the Fauves and German Expressionists in the early 20th century. Van Gogh's work gained widespread critical and commercial success in the following decades, and he has become a lasting icon of the romantic ideal of the tortured artist. Today, van Gogh's works are among the world's most expensive paintings ever sold. His legacy is celebrated by the Van Gogh Museum in Amsterdam, which holds the world's largest collection of his paintings and drawings.